Weight Loss Drugs can cause a Major Loss of Muscle Mass and Reduce Bone Density.

New weight loss drugs like Ozempic and Wegovy are helping thousands of people to lose weight, control diabetes and experience multiple health benefits.

However, along with these benefits comes a startling new drawback. Individuals of all ages taking these weight loss drugs have started to lose significant amounts of muscle mass along with the fat.

While weight loss can bring about health benefits, losing weight rapidly can also cause a decrease in muscle mass, lessen bone density, and lower your resting metabolic rate, leading to sarcopenia — the gradual loss of muscle mass, strength, and function.

Sarcopenia is usually associated with older individuals as the body naturally loses muscle as we age at rates that range from 3-8% per decade after 30. Muscle loss continues after the age of 50 at an even higher rate.

“According to a clinical trial of Ozempic, after 68 weeks on the medication, 86.4% of participants lost 5% or more of their body weight, and 69.1% lost 10% or more of their body weight.”

“Any time people lose weight, one-quarter to one-third of that weight can be muscle, and the faster we lose weight, the more likely we are to lose muscle. While 20% reduction in muscle mass seems normal for someone losing weight, the problem is the length of time in which this muscle loss occurs,” said Dr. Rekha Kumar, a practicing endocrinologist in NYC.

These trials show a potential for significant muscle loss for individuals using weight loss drugs which could open a door to many more health problems in the future.

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Reference: https://www.healthline.com/health-news/ozempic-muscle-mass-loss